Chronic immune activation and CD4+ Tcell lymphopenia in healthy African individuals: Perspectives for SARS-CoV-2 vaccine efficacy
Chronic immune activation has been considered as the driving force for CD4+ T cell depletion in people infected with HIV-1. Interestingly, the normal immune profile of adult HIV-negative individuals living in Africa also exhibit chronic immune activation, reminiscent of that observed in HIV-1 infect...
Main Authors: | , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Frontiers Media
2021
|