Chronic immune activation and CD4+ Tcell lymphopenia in healthy African individuals: Perspectives for SARS-CoV-2 vaccine efficacy

Chronic immune activation has been considered as the driving force for CD4+ T cell depletion in people infected with HIV-1. Interestingly, the normal immune profile of adult HIV-negative individuals living in Africa also exhibit chronic immune activation, reminiscent of that observed in HIV-1 infect...

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Bibliographic Details
Main Authors: Wolday, D, Ndungu, FM, Gómez-Pérez, GP, de Wit, TFR
Format: Journal article
Language:English
Published: Frontiers Media 2021

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