Distinct roles for the hypoxia-inducible transcription factors HIF-1alpha and HIF-2alpha in human osteoclast formation and function

Bone homeostasis is maintained by a balance between osteoblast-mediated bone formation and osteoclast-driven bone resorption. Hypoxia modulates this relationship partially via direct and indirect effects of the hypoxia-inducible factor-1 alpha (HIF-1α) transcription factor on osteoclast formation an...

תיאור מלא

מידע ביבליוגרפי
מחבר ראשי: Knowles, H
פורמט: Journal article
שפה:English
יצא לאור: Nature Research 2020