Cutting edge: back to "one-way" germinal centers.
The present status of germinal center (GC) research is revisited using in silico simulations based on recent lymphocyte motility data in mice. The generally adopted view of several rounds of somatic hypermutations and positive selection is analyzed with special emphasis on the spatial organization o...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2005
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