Expression of vascular Notch ligands Delta-like 4 and Jagged-1 in glioblastoma

Aims: The coordinated expression of the Notch ligands Delta-like 4 (Dll4) and Jagged (Jag)1 is believed to define appropriate endothelial sensitivity to vascular endothelial growth factor (VEGF). Preclinical data suggest that Dll4-Notch signalling may confer resistance to anti-VEGF therapy with beva...

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Bibliographic Details
Main Authors: Jubb, A, Browning, L, Campo, L, Turley, H, Steers, G, Thurston, G, Harris, A, Ansorge, O
Format: Journal article
Language:English
Published: 2012