Expression of vascular Notch ligands Delta-like 4 and Jagged-1 in glioblastoma
Aims: The coordinated expression of the Notch ligands Delta-like 4 (Dll4) and Jagged (Jag)1 is believed to define appropriate endothelial sensitivity to vascular endothelial growth factor (VEGF). Preclinical data suggest that Dll4-Notch signalling may confer resistance to anti-VEGF therapy with beva...
Hauptverfasser: | , , , , , , , |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2012
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