Regulation of translesion synthesis DNA polymerase eta by monoubiquitination.
DNA polymerase eta is a Y family polymerase involved in translesion synthesis (TLS). Its action is initiated by simultaneous interaction between the PIP box in pol eta and PCNA and between the UBZ in pol eta and monoubiquitin attached to PCNA. Whereas monoubiquitination of PCNA is required for its i...
Main Authors: | , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2010
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