Design of a calcium-binding protein with desired structure in a cell adhesion molecule.

Ca2+, "a signal of life and death", controls numerous cellular processes through interactions with proteins. An effective approach to understanding the role of Ca2+ is the design of a Ca2+-binding protein with predicted structural and functional properties. To design de novo Ca2+-binding s...

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Bibliographic Details
Main Authors: Yang, W, Wilkins, A, Ye, Y, Liu, Z, Li, S, Urbauer, J, Hellinga, H, Kearney, A, Van Der Merwe, P, Yang, J
Format: Journal article
Language:English
Published: 2005