Failure of glucose to elicit a normal secretory response in fetal pancreatic beta cells results from glucose insensitivity of the ATP-regulated K+ channels.
Fetal pancreatic beta cells demonstrate a deficient insulin release in response to glucose, but the underlying mechanism at the cellular level is unknown. By using beta cells from 21-day fetal rats we made an attempt to clarify the mechanism(s) behind this reduced glucose response. In addition to me...
主要な著者: | Rorsman, P, Arkhammar, P, Bokvist, K, Hellerström, C, Nilsson, T, Welsh, M, Welsh, N, Berggren, P |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
1989
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