Failure of glucose to elicit a normal secretory response in fetal pancreatic beta cells results from glucose insensitivity of the ATP-regulated K+ channels.

Failure of glucose to elicit a normal secretory response in fetal pancreatic beta cells results from glucose insensitivity of the ATP-regulated K+ channels.

Fetal pancreatic beta cells demonstrate a deficient insulin release in response to glucose, but the underlying mechanism at the cellular level is unknown. By using beta cells from 21-day fetal rats we made an attempt to clarify the mechanism(s) behind this reduced glucose response. In addition to me...

Полное описание

Библиографические подробности
Главные авторы:	Rorsman, P, Arkhammar, P, Bokvist, K, Hellerström, C, Nilsson, T, Welsh, M, Welsh, N, Berggren, P
Формат:	Journal article
Язык:	English
Опубликовано:	1989

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