Systemic regulation of vascular NAD(P)H oxidase activity and nox isoform expression in human arteries and veins.

OBJECTIVE: Impaired endothelial function, characterized by nitric oxide scavenging by increased superoxide production, is a hallmark of vascular disease states. However, molecular mechanisms regulating superoxide production in human blood vessels remain poorly defined. METHODS AND RESULTS: We compa...

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Bibliographic Details
Main Authors: Guzik, T, Sadowski, J, Kapelak, B, Jopek, A, Rudzinski, P, Pillai, R, Korbut, R, Channon, K
Format: Journal article
Language:English
Published: 2004