Natural history of GATA1 mutations in Down syndrome.

Natural history of GATA1 mutations in Down syndrome.

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Acquired mutations in megakaryocyte transcription factor GATA1 have recently been reported in Down syndrome (DS), transient myeloproliferative disorder (TMD), and acute megakaryoblastic leukemia (AMKL). To provide novel insight into GATA1 mutations in DS, genomic DNA was assayed from 12 AMKL and 4 T...

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Bibliographic Details
Main Authors: Ahmed, M, Sternberg, A, Hall, G, Thomas, A, Smith, O, O'Marcaigh, A, Wynn, R, Stevens, R, Addison, M, King, D, Stewart, B, Gibson, B, Roberts, I, Vyas, P
Format: Journal article
Language:English
Published: 2004

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