Restoration of cone vision in the CNGA3-/- mouse model of congenital complete lack of cone photoreceptor function.

Congenital absence of cone photoreceptor function is associated with strongly impaired daylight vision and loss of color discrimination in human achromatopsia. Here, we introduce viral gene replacement therapy as a potential treatment for this disease in the CNGA3(-/-) mouse model. We show that such...

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Bibliographic Details
Main Authors: Michalakis, S, Mühlfriedel, R, Tanimoto, N, Krishnamoorthy, V, Koch, S, Fischer, M, Becirovic, E, Bai, L, Huber, G, Beck, S, Fahl, E, Büning, H, Paquet-Durand, F, Zong, X, Gollisch, T, Biel, M, Seeliger, M
Format: Journal article
Language:English
Published: 2010