Assessment of acute bowel toxicity from chemoradiation for bladder cancer using an in vivo gastrointestinal crypt assay and in vitro organoid system

Radiotherapy combined with a radiosensitiser is effective treatment in muscle-invasive bladder cancer, but can result in severe bowel toxicity. The classical crypt assay can be used to assess gut toxicity in vivo following whole abdominal radiation. The recent development of delivering focussed radi...

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Bibliographic Details
Main Authors: Gorrill, J, Ruan, J, Groselj, B, Hsu, J, Scudamore, C, Kiltie, A
Format: Conference item
Published: Elsevier 2017