Assessment of acute bowel toxicity from chemoradiation for bladder cancer using an in vivo gastrointestinal crypt assay and in vitro organoid system
Radiotherapy combined with a radiosensitiser is effective treatment in muscle-invasive bladder cancer, but can result in severe bowel toxicity. The classical crypt assay can be used to assess gut toxicity in vivo following whole abdominal radiation. The recent development of delivering focussed radi...
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Elsevier
2017
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