Oxygen sensing in cancer.
Hypoxia is prevalent in many tumours and is prognostically important. A transcriptional pathway controlled by hypoxia-inducible factor-1 (HIF) is also commonly up-regulated in cancer, resulting in the induction of genes with both pro- and anti-tumourigenic properties. High HIF levels may arise as a...
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| Aineistotyyppi: | Journal article |
| Kieli: | English |
| Julkaistu: |
2003
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