Synthetic α- and β-Ser-ADP-ribosylated peptides reveal α-Ser-ADPr as the native epimer

A solid-phase methodology to synthesize oligopeptides, specifically incorporating serine residues linked to ADP-ribose (ADPr), is presented. Through the synthesis of both α- and β-anomers of the phosphoribosylated Fmoc-Ser building block and their usage in our modified solid-phase peptide synthesis...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Voorneveld, J, Rack, J, Ahel, I, Overkleeft, H, van der Marel, G, Filippov, D
Aineistotyyppi: Journal article
Julkaistu: American Chemical Society 2018