Lysosome-dependent pathways as a unifying theme in Parkinson's disease.

Although the pathogenesis of Parkinson's disease (PD) is considered multifactorial, evidence from genetics and cell biology has implicated specific molecular pathways. This article summarizes evidence that suggests that the level of intracellular alpha-synuclein is critical for the onset of neu...

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Autore principale: Tofaris, G
Natura: Journal article
Lingua:English
Pubblicazione: 2012