CRISPRi: a way to integrate iPSC-derived neuronal models

The genetic landscape of neurodegenerative diseases encompasses genes affecting multiple cellular pathways which exert effects in an array of neuronal and glial cell-types. Deconvolution of the roles of genes implicated in disease and the effects of disease-associated variants remains a vital step i...

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Xehetasun bibliografikoak
Egile Nagusiak: Franks, SNJ, Heon-Roberts, R, Ryan, B
Formatua: Journal article
Hizkuntza:English
Argitaratua: Portland Press 2024