Towards the elucidation of the mechanism of action of small molecule upregulators of utrophin using chemical proteomics

<p>Duchenne Muscular Dystrophy (DMD) is an X-linked recessive and progressive muscle-wasting disease caused by a lack of the cytoskeletal protein dystrophin. There is currently no disease modifying treatment for all patients, although various promising approaches (e.g. exon skipping, read thro...