N-butyldeoxynojirimycin causes weight loss as a result of appetite suppression in lean and obese mice.

AIM: To determine the mechanism of weight loss caused by high doses of N-butyldeoxynojirimycin (NB-DNJ) in healthy lean and leptin-deficient obese (ob/ob) mice. METHODS: Healthy lean and obese mice were treated with NB-DNJ by the following methods: admixed with their diet, delivered by subcutaneous...

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Bibliographic Details
Main Authors: Priestman, D, van der Spoel, A, Butters, T, Dwek, R, Platt, F
Format: Journal article
Language:English
Published: 2008