Type 1 IGF receptor associates with adverse outcome and cellular radioresistance in paediatric high-grade glioma

High-grade glioma (HGG) is highly resistant to therapy, prompting us to investigate the contribution of insulin-like growth factor receptor (IGF-1R), linked with radioresistance in other cancers. IGF-1R immunohistochemistry in 305 adult HGG (aHGG) and 103 paediatric/young adult HGG (pHGG) cases reve...

Full description

Bibliographic Details
Main Authors: Simpson, A, Wei Soo, Y, Rieunier, G, Aleksic, T, Ansorge, O, Jones, C, Macaulay, V
Format: Journal article
Language:English
Published: Springer Nature 2019