Type 1 IGF receptor associates with adverse outcome and cellular radioresistance in paediatric high-grade glioma

High-grade glioma (HGG) is highly resistant to therapy, prompting us to investigate the contribution of insulin-like growth factor receptor (IGF-1R), linked with radioresistance in other cancers. IGF-1R immunohistochemistry in 305 adult HGG (aHGG) and 103 paediatric/young adult HGG (pHGG) cases reve...

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Main Authors: Simpson, A, Wei Soo, Y, Rieunier, G, Aleksic, T, Ansorge, O, Jones, C, Macaulay, V
格式: Journal article
语言:English
出版: Springer Nature 2019