Contributions of COMT and DAT to regulation of phasic dopamine release and reward-guided behaviour
<p>Fine temporal regulation of dopamine transmission is critical to its effects on behaviour. Dopamine can be cleared from the synapse either by recycling via the dopamine transporter (DAT) or by enzymatic degradation involving catechol-O-methyltransferase (COMT). DAT recycling predominates...
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Format: | Thesis |
Language: | English |
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2016
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