High dose ursodeoxycholic acid for the treatment of primary sclerosing cholangitis is safe and effective.

BACKGROUND/AIMS: Ursodeoxycholic acid (UDCA) has been shown to improve serum liver tests in primary sclerosing cholangitis (PSC), but controlled trials have shown inconsistent effects on liver histology, and did not reveal a survival benefit. This pilot, randomised dose-ranging trial attempted to d...

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Bibliografische gegevens
Hoofdauteurs: Cullen, SN, Rust, C, Fleming, K, Edwards, C, Beuers, U, Chapman, R
Formaat: Journal article
Taal:English
Gepubliceerd in: 2008