Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure.

BACKGROUND: Two single-nucleotide polymorphisms, rs1051730 and rs16969968, located within the nicotinic acetylcholine receptor gene cluster on chromosome 15q25 locus, are associated with heaviness of smoking, risk for lung cancer, and other smoking-related health outcomes. Previous studies have typi...

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Bibliographic Details
Main Authors: Munafò, MR, Timofeeva, M, Morris, R, Prieto-Merino, D, Sattar, N, Brennan, P, Johnstone, E, Relton, C, Johnson, P, Walther, D, Whincup, P, Casas, J, Uhl, G, Vineis, P, Padmanabhan, S, Jefferis, B, Amuzu, A, Riboli, E, Upton, M, Aveyard, P, Ebrahim, S, Hingorani, A, Watt, G, Palmer, T, Timpson, N, Davey Smith, G
Format: Journal article
Language:English
Published: 2012