PET imaging of DNA damage using 89Zr-labelled anti-γH2AX-TAT immunoconjugates
© 2015, Springer-Verlag Berlin Heidelberg. Purpose: The efficacy of most anticancer treatments, including radiotherapy, depends on an ability to cause DNA double-strand breaks (DSBs). Very early during the DNA damage signalling process, the histone isoform H2AX is phosphorylated to form γH2AX. With...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Journal article |
| Published: |
2015
|