Regulation of major histocompatibility complex class II gene expression, genetic variation and disease.
Major histocompatibility complex (MHC) class II molecules are central to adaptive immune responses and maintenance of self-tolerance. Since the early 1970s, the MHC class II region at chromosome 6p21 has been shown to be associated with a remarkable number of autoimmune, inflammatory and infectious...
Main Authors: | Handunnetthi, L, Ramagopalan, S, Ebers, G, Knight, J |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
2010
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