Regulation of major histocompatibility complex class II gene expression, genetic variation and disease.

Major histocompatibility complex (MHC) class II molecules are central to adaptive immune responses and maintenance of self-tolerance. Since the early 1970s, the MHC class II region at chromosome 6p21 has been shown to be associated with a remarkable number of autoimmune, inflammatory and infectious...

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Hlavní autoři: Handunnetthi, L, Ramagopalan, S, Ebers, G, Knight, J
Médium: Journal article
Jazyk:English
Vydáno: 2010