Thymic involution and rising disease incidence with age.

Thymic involution and rising disease incidence with age.

For many cancer types, incidence rises rapidly with age as an apparent power law, supporting the idea that cancer is caused by a gradual accumulation of genetic mutations. Similarly, the incidence of many infectious diseases strongly increases with age. Here, combining data from immunology and epide...

書誌詳細
主要な著者:	Palmer, S, Albergante, L, Blackburn, CC, Newman, TJ
フォーマット:	Journal article
言語:	English
出版事項:	National Academy of Sciences 2018

類似資料

Reply to Jiménez-Alonso et al., Schooling and Zhao, and Mortazavi: Further discussion on the immunological model of carcinogenesis
著者:: Palmer, S, 等
出版事項: (2018)

Human Thymic Involution and Aging in Humanized Mice
著者:: Qing-Yue Tong, 等
出版事項: (2020-07-01)

Contributions of Age-Related Thymic Involution to Immunosenescence and Inflammaging
著者:: Rachel Thomas, 等
出版事項: (2020-01-01)

MicroRNA Functions in Thymic Biology: Thymic Development and Involution
著者:: Minwen Xu, 等
出版事項: (2018-09-01)

Foxn1 Is Dynamically Regulated in Thymic Epithelial Cells during Embryogenesis and at the Onset of Thymic Involution.
著者:: Kathy E O'Neill, 等
出版事項: (2016-01-01)

Peripubertal orchidectomy transitorily affects age-associated thymic involution in rats
著者:: V. Pesic, 等
出版事項: (2007-11-01)

MicroRNAs Regulate Thymic Epithelium in Age-Related Thymic Involution via Down- or Upregulation of Transcription Factors
著者:: Minwen Xu, 等
出版事項: (2017-01-01)

Overexpression of lymphotoxin in T cells induces fulminant thymic involution.
著者:: Heikenwalder, M, 等
出版事項: (2008)

Tyrosine phosphorylation related to thymic involution induced by diet restriction in comparison with aging
著者:: Izumi Takase
出版事項: (2020-12-01)

TGF- 2signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution
著者:: Hauri-Hohl, M, 等
出版事項: (2008)

TGF-beta signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution.
著者:: Hauri-Hohl, M, 等
出版事項: (2008)

Thymus ad astra, or spaceflight-induced thymic involution
著者:: Wataru Muramatsu, 等
出版事項: (2025-01-01)

Multiple thymi and no thymic involution in naked mole rats?
著者:: Graham Pawelec
出版事項: (2021-11-01)

Global Transcriptional Profiling Reveals Distinct Functions of Thymic Stromal Subsets and Age-Related Changes during Thymic Involution
著者:: Sanghee Ki, 等
出版事項: (2014-10-01)

Lin28 regulates thymic growth and involution and correlates with MHCII expression in thymic epithelial cells
著者:: Shiyun Xiao, 等
出版事項: (2023-10-01)

Dendritic cell-intrinsic Ezh2 expression maintains thymic homeostasis and prevents premature thymic involution
著者:: Sint Thida Bo
出版事項: (2023)

Transcriptional profile of human thymus reveals IGFBP5 is correlated with age-related thymic involution
著者:: Xiaojing Yang, 等
出版事項: (2024-01-01)

Aging augments obesity-induced thymic involution and peripheral T cell exhaustion altering the “obesity paradox”
著者:: Logan V. Vick, 等
出版事項: (2023-01-01)

Alterations of Thymic Epithelial Cells in Lipopolysaccharide-induced Neonatal Thymus Involution
著者:: Yong-Jie Zhou, 等
出版事項: (2016-01-01)

COVID-19 hospitalization rates rise exponentially with age, inversely proportional to thymic T-cell production
著者:: Palmer, S, 等
出版事項: (2021)

Systemic immunostimulation induces glucocorticoid-mediated thymic involution succeeded by rebound hyperplasia which is impaired in aged recipients
著者:: Craig P. Collins, 等
出版事項: (2024-09-01)

IL-33 induces thymic involution-associated naive T cell aging and impairs host control of severe infection
著者:: Lei Xu, 等
出版事項: (2022-11-01)

The effect of age on thymic function
著者:: Donald B. Palmer
出版事項: (2013-10-01)

A Proposed Link Between Acute Thymic Involution and Late Adverse Effects of Chemotherapy
著者:: Maria K. Lagou, 等
出版事項: (2022-07-01)

Are zinc-bound metallothionein isoforms (I+II and III) involved in impaired thymulin production and thymic involution during ageing?
著者:: Cipriano Catia, 等
出版事項: (2004-11-01)

Abrogation of Notch Signaling in Embryonic TECs Impacts Postnatal mTEC Homeostasis and Thymic Involution
著者:: María Jesús García-León, 等
出版事項: (2022-05-01)

Thymic Involution and Altered Naive CD4 T Cell Homeostasis in Neuromyelitis Optica Spectrum Disorder
著者:: Haoxiao Chang, 等
出版事項: (2021-07-01)

Nuclear Progesterone Receptor Expressed by the Cortical Thymic Epithelial Cells Dictates Thymus Involution in Murine Pregnancy
著者:: Soo Hyun Ahn, 等
出版事項: (2022-04-01)

Expression of the HPV16E7 Oncoprotein by Thymic Epithelium is Accompanied by Disrupted T Cell Maturation and a Failure of the Thymus to Involute with Age
著者:: I. H. Frazer, 等
出版事項: (2003-01-01)

In vitro fertilization pregnancy may cause fetal thymic volume involution: A case-control study
著者:: Nurgul Selin Kaya, 等
出版事項: (2023-11-01)

Thymic involution caused by repeated cocaine administration includes apoptotic cell loss followed by ectopic adipogenesis.
著者:: Kana Unuma, 等
出版事項: (2022-01-01)

Thymic involution caused by repeated cocaine administration includes apoptotic cell loss followed by ectopic adipogenesis
著者:: Kana Unuma, 等
出版事項: (2022-01-01)

Corrigendum: Nuclear Progesterone Receptor Expressed by the Cortical Thymic Epithelial Cells Dictates Thymus Involution in Murine Pregnancy
著者:: Soo Hyun Ahn, 等
出版事項: (2022-06-01)

The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor.
著者:: Papadopoulou, A, 等
出版事項: (2012)

Thymic epithelial organoids mediate T-cell development
著者:: Hübscher, T, 等
出版事項: (2024)

Trends in the incidence of thymoma, thymic carcinoma, and thymic neuroendocrine tumor in the United States.
著者:: Chun-Hsiang Hsu, 等
出版事項: (2019-01-01)

Postnatal Involution and Counter-Involution of the Thymus
著者:: Jennifer E. Cowan, 等
出版事項: (2020-05-01)

Circulating mature dendritic cells homing to the thymus promote thymic epithelial cells involution via the Jagged1/Notch3 axis
著者:: Haojie Wu, 等
出版事項: (2021-08-01)

Incidence, mortality, and survival analyses of patients with thymic lymphoma
著者:: Li Wang, 等
出版事項: (2022-09-01)

Transcriptome analysis reveals a potential regulatory mechanism of the lnc-5423.6/IGFBP5 axis in the early stages of mouse thymic involution
著者:: Li Bingxin, 等
出版事項: (2023-04-01)