Ana1 helps recruit Polo to centrioles to promote mitotic PCM assembly and centriole elongation

Polo kinase (PLK1 in mammals) is a master cell cycle regulator that is recruited to various subcellular structures, often by its polo-box domain (PBD), which binds to phosphorylated S-pS/pT motifs. Polo/PLK1 kinases have multiple functions at centrioles and centrosomes, and we have previously shown...

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Bibliographic Details
Main Authors: Alvarez-Rodrigo, I, Wainman, A, Saurya, S, Raff, JW
Format: Journal article
Language:English
Published: Company of Biologists 2021