Differential role of the influenza A virus polymerase PA subunit for vRNA and cRNA promoter binding.

The RNA polymerase of influenza A virus is a heterotrimeric complex of PB1, PB2 and PA subunits that is required for transcription and replication of the viral genome. Here, we demonstrate a differential requirement of the PA subunit for binding to the vRNA and cRNA promoters--specifically, PA is mo...

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Detalhes bibliográficos
Principais autores: Maier, H, Kashiwagi, T, Hara, K, Brownlee, G
Formato: Journal article
Idioma:English
Publicado em: 2008