Differential role of the influenza A virus polymerase PA subunit for vRNA and cRNA promoter binding.
The RNA polymerase of influenza A virus is a heterotrimeric complex of PB1, PB2 and PA subunits that is required for transcription and replication of the viral genome. Here, we demonstrate a differential requirement of the PA subunit for binding to the vRNA and cRNA promoters--specifically, PA is mo...
Principais autores: | , , , |
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Formato: | Journal article |
Idioma: | English |
Publicado em: |
2008
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