Differential role of the influenza A virus polymerase PA subunit for vRNA and cRNA promoter binding.

Differential role of the influenza A virus polymerase PA subunit for vRNA and cRNA promoter binding.

The RNA polymerase of influenza A virus is a heterotrimeric complex of PB1, PB2 and PA subunits that is required for transcription and replication of the viral genome. Here, we demonstrate a differential requirement of the PA subunit for binding to the vRNA and cRNA promoters--specifically, PA is mo...

Полное описание

Библиографические подробности
Главные авторы:	Maier, H, Kashiwagi, T, Hara, K, Brownlee, G
Формат:	Journal article
Язык:	English
Опубликовано:	2008

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