STEPWISE HYDROGEN REMOVAL IN THE ENZYMATIC RING EXPANSION OF PENICILLIN-N TO DEACETOXYCEPHALOSPORIN-C

Reaction of a 1:1 mixture of penicillin N and 2,2-bis(trideuteriomethyl) penicillin N with partially purified deacetoxy-cephalosporin C/deacetylcephalosporin C synthetase from Cephalosporium acremonium CO 728 resulted in preferential conversion of the protiated substrate, whereas in similar experime...

詳細記述

書誌詳細
主要な著者: Baldwin, J, Adlington, R, Aplin, R, Crouch, N, Schofield, C, Ting, H
フォーマット: Journal article
言語:English
出版事項: 1987