Peroxynitrite activated drug conjugate systems based on a coumarin scaffold toward the application of theranostics

Two novel drug-conjugates based on a “coumarin linker” have been designed for the synergic release of a therapeutic agent and fluorescent probe for the potential application of theranostics. The drug conjugates; CC-RNS and CI-RNS were designed to be activated by reactive oxygen species or reactive n...

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Bibliographic Details
Main Authors: Odyniec, M, Han, H, Gardiner, J, Sedgwick, A, He, X, Bull, S, James, T
Format: Journal article
Language:English
Published: Frontiers Media 2019