Peroxynitrite activated drug conjugate systems based on a coumarin scaffold toward the application of theranostics
Two novel drug-conjugates based on a “coumarin linker” have been designed for the synergic release of a therapeutic agent and fluorescent probe for the potential application of theranostics. The drug conjugates; CC-RNS and CI-RNS were designed to be activated by reactive oxygen species or reactive n...
Main Authors: | Odyniec, M, Han, H, Gardiner, J, Sedgwick, A, He, X, Bull, S, James, T |
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Format: | Journal article |
Language: | English |
Published: |
Frontiers Media
2019
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