Energetics of ion permeation in an open-activated TRPV1 channel.

Ion channels enable diffusion of ions down physiological electrochemical gradients. Modulation of ion permeation is crucial for the physiological functioning of cells, and misregulation of ion channels is linked to a myriad of channelopathies. The ion permeation mechanism in the transient receptor p...

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Bibliographic Details
Main Authors: Jorgensen, C, Furini, S, Domene, C
Format: Journal article
Language:English
Published: Elsevier 2016