ChAdOx1 nCoV-19 protection against SARS-CoV-2 in rhesus macaque and ferret challenge models

Vaccines against SARS-CoV-2 are urgently required, but early development of vaccines against SARS-CoV-1 resulted in enhanced disease after vaccination. Careful assessment of this phenomena is warranted for vaccine development against SARS CoV-2. Here we report detailed immune profiling after ChAdOx1...

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Bibliographic Details
Main Authors: Lambe, T, Spencer, AJ, Thomas, KM, Gooch, KE, Thomas, S, White, AD, Humphries, HE, Wright, D, Belij-Rammerstorfer, S, Thakur, N, Conceicao, C, Watson, R, Alden, L, Allen, L, Aram, M, Bewley, KR, Brunt, E, Brown, P, Cavell, BE, Cobb, R, Fotheringham, SA, Gilbride, C, Harris, DJ, Ho, CMK, Hunter, L, Kennard, CL, Leung, S, Lucas, V, Ngabo, D, Ryan, KA, Sharpe, H, Sarfas, C, Sibley, L, Slack, GS, Ulaszewska, M, Wand, N, Wiblin, NR, Gleeson, FV, Bailey, D, Sharpe, S, Charlton, S, Salguero, FJ, Carroll, MW, Gilbert, SC
Format: Journal article
Language:English
Published: Springer Nature 2021