GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function.

OBJECTIVES: This study sought to determine the effects of endogenous tetrahydrobiopterin (BH4) bioavailability on endothelial nitric oxide synthase (eNOS) coupling, nitric oxide (NO) bioavailability, and vascular superoxide production in patients with coronary artery disease (CAD). BACKGROUND: GTP-c...

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Bibliographic Details
Main Authors:	Antoniades, C, Shirodaria, C, Van Assche, T, Cunnington, C, Tegeder, I, Lötsch, J, Guzik, T, Leeson, P, Diesch, J, Tousoulis, D, Stefanadis, C, Costigan, M, Woolf, C, Alp, N, Channon, K
Format:	Journal article
Language:	English
Published:	2008

GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function.

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