MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction.

Antigen presentation to T cells by MHC molecules is essential for adaptive immune responses. To determine the exact position of a gene affecting expression of MHC molecules, we finely mapped a previously defined rat quantitative trait locus regulating MHC class II on microglia in an advanced intercr...

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Autors principals: Swanberg, M, Lidman, O, Padyukov, L, Eriksson, P, Akesson, E, Jagodic, M, Lobell, A, Khademi, M, Börjesson, O, Lindgren, C, Lundman, P, Brookes, A, Kere, J, Luthman, H, Alfredsson, L, Hillert, J, Klareskog, L, Hamsten, A, Piehl, F, Olsson, T
Format: Journal article
Idioma:English
Publicat: 2005