A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets

Exosomal miRNA transfer is a mechanism for cell-cell communication that is important in the immune response, in the functioning of the nervous system and in cancer. Syncrip/hnRNPQ is a highly conserved RNA-binding protein that mediates the exosomal partition of a set of miRNAs. Here, we report that...

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Bibliographic Details
Main Authors: Hobor, F, Dallmann, A, Ball, NJ, Cicchini, C, Battistelli, C, Ogrodowicz, RW, Christodoulou, E, Martin, SR, Castello, A, Tripodi, M, Taylor, IA, Ramos, A
Format: Journal article
Published: Nature Publishing Group 2018