The unfolded protein response: a novel therapeutic target for poor prognostic BRAF mutant colorectal cancer
BRAFV600E mutations occur in 10% of colorectal cancer (CRC) cases, are associated with poor survival and have limited responses to BRAF/MEK inhibition with or without EGFR inhibition. There is an unmet need to understand the biology of poor prognostic BRAFMT CRC. We have used differential gene expre...
| Autors principals: | , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Idioma: | English |
| Publicat: |
American Association for Cancer Research
2018
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