Improving orthogonality in two-component biological signalling systems using feedback control

In natural biological systems, cellular responses to changing growth and environmental conditions are governed by complex signalling and control networks. A common signalling motif is that of the two component signalling systems (TCSSs), dozens of which may operate simultaneously in a single cell. W...

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Bibliographic Details
Main Authors: Steel, H, Sootla, A, Smart, B, Delalez, N, Papachristodoulou, A
Format: Journal article
Published: IEEE 2018