The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36.

Post-translational modification of chromatin has profound effects on many biological processes including transcriptional regulation, heterochromatin organization, and X-chromosome inactivation. Recent studies indicate that methylation on specific histone lysine (K) residues participates in many of t...

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Bibliographic Details
Main Authors: Klose, R, Yamane, K, Bae, Y, Zhang, D, Erdjument-Bromage, H, Tempst, P, Wong, J, Zhang, Y
Format: Journal article
Language:English
Published: 2006