Hepatitis C virus glycoprotein E2 binding to CD81: the role of E1E2 cleavage and protein glycosylation in bioactivity.

The hepatitis C virus glycoproteins E1 and 2 have been expressed using recombinant baculoviruses following fusion to the carrier protein glutathione S-transferase (GST). Proteins were expressed singly and as an E1E2 polyprotein with and without an N-terminal affinity tag. Expression of the E1E2 poly...

Full description

Bibliographic Details
Main Authors: Chan-Fook, C, Jiang, W, Clarke, B, Zitzmann, N, Maidens, C, McKeating, J, Jones, I
Format: Journal article
Language:English
Published: Elsevier 2000