Salmonella typhi bactericidal antibodies reduce disease severity but do not protect against typhoid fever in a controlled human infection model

Effective vaccines against Salmonella Typhi, a major cause of febrile illness in tropical regions, can have a significant effect as a disease control measure. Earlier work has shown that immunization with either of two Salmonella Typhi vaccines, licensed Ty21a or candidate M01ZH09, did not provide f...

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Détails bibliographiques
Auteurs principaux: Juel, H, Thomaides-Brears, H, Darton, T, Jones, C, Jones, E, Shrestha, S, Sie, R, Eustace, A, Galal, U, Kurupati, P, Van, T, Thieu, N, Baker, S, Blohmke, C, Pollard, A
Format: Journal article
Publié: Frontiers Media 2018