Crotonases: Nature’s exceedingly convertible catalysts
The crotonases comprise a widely distributed enzyme superfamily that has multiple roles in both primary and secondary metabolism. Many crotonases employ oxyanion holemediated stabilization of intermediates to catalyze the reaction of coenzyme A (CoA) thioester substrates (e.g., malonyl-CoA, a,β- uns...
主要な著者: | Lohans, C, Wang, D, Wang, J, Hamed, R, Schofield, C |
---|---|
フォーマット: | Journal article |
出版事項: |
American Chemical Society
2017
|
類似資料
-
Mechanisms and structures of crotonase superfamily enzymes--how nature controls enolate and oxyanion reactivity.
著者:: Hamed, R, 等
出版事項: (2008) -
Use of methylmalonyl‐CoA epimerase in enhancing crotonase stereoselectivity
著者:: Hamed, R, 等
出版事項: (2015) -
Crotonase catalysis enables flexible production of functionalized prolines and carbapenams.
著者:: Hamed, R, 等
出版事項: (2012) -
Thioester hydrolysis and C-C bond formation by carboxymethylproline synthase from the crotonase superfamily.
著者:: Batchelar, E, 等
出版事項: (2008) -
Biocatalytic production of bicyclic β-lactams with three contiguous chiral centres using engineered crotonases
著者:: Hamed, R, 等
出版事項: (2019)