Tetrameric structure of SUR2B revealed by electron microscopy of oriented single particles

The ATP-sensitive potassium (KATP) channel is a hetero-octameric complex that links cell metabolism to membrane electrical activity in many cells, thereby controlling physiological functions such as insulin release, muscle contraction and neuronal activity. It consists of four pore-forming Kir6.2 an...

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Bibliographic Details
Main Authors: Fotinou, C, Aittoniemi, J, De Wet, H, Polidori, A, Pucci, B, Sansom, M, Vénien-Bryan, C, Ashcroft, F
Format: Journal article
Language:English
Published: 2013