Pneumococcal genome sequencing tracks a vaccine escape variant formed through a multi-fragment recombination event

Streptococcus pneumoniae ('pneumococcus') causes an estimated 14.5 million cases of serious disease and 826,000 deaths annually in children under 5 years of age. The highly effective introduction of the PCV7 pneumococcal vaccine in 2000 in the United States provided an unprecedented opport...

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Bibliographic Details
Main Authors: Golubchik, T, Brueggemann, AB, Street, T, Gertz, R, Spencer, C, Ho, T, Giannoulatou, E, Link-Gelles, R, Harding, R, Beall, B, Peto, T, Moore, MR, Donnelly, P, Crook, D, Bowden, R
Format: Journal article
Language:English
Published: 2012