Interplay of two major repair pathways in the processing of complex double-strand DNA breaks.

Radiation-induced complex double-strand breaks (DSBs) characterised by base lesions, abasic sites or single-strand breaks in close proximity to the break termini, are believed to be a major cause of the biological effects of ionising radiation exposure. It has been hypothesised that complex DSBs pos...

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Bibliographic Details
Main Authors: Dobbs, T, Palmer, P, Maniou, Z, Lomax, M, O'Neill, P
Format: Journal article
Language:English
Published: 2008